Frederick Boop, MD
Disclosures: Nothing to disclose


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BOOP, Frederick Alan


Professor and J.T. Robertson Chair

Department of Neurosurgery

University of Tennessee Health Science Center

Semmes-Murphey Clinic


ERA COMMONS USER NAME (credential, e.g., agency login)


EDUCATION/TRAINING  (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable.)



(if applicable)



University of Arkansas, Fayetteville, Arkansas




University of Arkansas, Little Rock, Arkansas




University of Texas Health Science Center, San Antonio, Texas



General Surgery

University of Texas Health Science Center, San Antonio, Texas




National Hospital, Queen's Square, London, UK




Hospital for Sick Children, Toronto, Ontario, Canada



Pediatric Neurosurgery

University of Minnesota, Minneapolis, Minnesota



Epilepsy & Functional Neurosurgery

Arkansas Children's Hospital, Little Rock, Arkansas



Pediatric Neurosurgery




A.              Personal Statement


I have a 25 year history of serving as a professor of medical education in the university setting.  In that capacity I have taught medical students, graduate students, residents and fellows. I have also served as a mentor for junior faculty.  I have won several teaching awards both from medical students and residents for teaching abilities. I have served as a mentor for the POE program for the past four years.  I currently serve as chairman of the Department of Neurosurgery at the University of Tennessee Health Science Center. 


B.              Positions and Honors

Positions and Employment

1989-1990              Clinical Instructor, University of Arkansas for Medical Sciences, Little Rock, Arkansas

1990-1995              Assistant Professor, Neurosurgery and Anatomy, University of Arkansas for Medical Science, Little Rock, Arkansas

1991-1992              Vice-Chief, Division of Pediatric Neurosurgery, Arkansas Children's Hospital, Little Rock, Arkansas

1992-1998              Chief, Division of Pediatric Neurosurgery, Arkansas Children's Hospital, Little Rock, Arkansas

1995-1998              Associate Professor with Tenure, Departments of Neurosurgery and Anatomy, University of Arkansas for Medical Sciences, Little Rock, Arkansas

1998--2012              Chief Division of Pediatric Neurosurgery, LeBonheur Children's Medical Center, Memphis, Tennessee

2010                     St. Jude Endowed Chair in Neurosurgery

2010-Present              Chief Pediatric Neurosurgery, St. Jude Children's Research Hospital, Memphis, Tennessee

2011-Present              Professor and Chairman, Department of Neurosurgery, The University of Tennessee, Semmes-Murphey Clinic, Memphis, Tennessee

2016-present              Chairman, American Board of Pediatric Neurological Surgeons

2016-2017              President, American Association of Neurological Surgeons (AANS)

2017-present              Director, American Board of Neurological Surgeons

2017-present              Chairman, Audit Committee, World Federation of Neurological Surgeons

2017-present              Chairman, Audit Committee, International Society of Pediatric Neurosurgeons



Other Experience and Professional Memberships

Past President- Southern Neurosurgical Society

Past President - American Society of Pediatric Neurosurgeons

Past Treasurer - International Society of Pediatric Neurosurgery

Present - Board of Directors, American Association of Neurological Surgeons

Past Secretary - American Association of Neurological Surgeons

Past – President Elect American Association of Neurological Surgeons

Present – Chairman American Board of Pediatric Neurosurgery

Present – President American Association of Neurological Surgeons

Present-Member, World Academy of Neurological Surgeons




C.              Selected Peer-Reviewed Publications (in chronological order)


Neuroimaging detected late transient treatment-induced lesions in pediatric patients with brain tumors. Helton KJ, Edwards M, Steen GR, Merchant TE, Sapp MV, Boop FA, Langston J. J Neurosurg (Pediatrics 2) 102:179-186, 2005.


              Long-term outcome in patients harboring intracranial ependymoma.  J Neurosurg 103(1):4-5, 2005.

              Newman LA, Boop FA, Duntsch C, Keckley C, Sanford RA.  Post-operative swallowing function after posterior

              fossa tumor resection in pediatric patients. J Neurosurg (Pediatrics) Child’s Nerv Syst 22:1296-1300, 2006.


              Seizures in children with low-grade tumors: Outcome after tumor resection and risk factors for uncontrolled seizures. Khan RB, Boop FA, Onar A, Sanford RA.  J Neurosurg 104(6 Suppl):377-382, 2006.


              Phase II trial of conformal radiation therapy for pediatric patients with craniopharyngioma and correlation of surgical factors and radiation dosimetry with change in cognitive function. Merchant TE, Kiehna EN, Kun LE, Mulhern RK, Li C,  Xiong X, Boop FA, Sanford RA.  J Neurosurg 104(2 Suppl):94-102, 2006.


Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. North PA, Nakahara Y, Wu X, Feuk L, Ellison DW, Croul S, Mack S, Kongkham PN, Peacock J, Dubuc A, Ra YS, Zilberberg K, McLeod J, Scherer SW, Sunil Rao J, Eberhart CG, Grajkowska W, Gillespie Y, Lach B, Grundy R, Pollack IF, Hamilton RL, Van Meter T, Carlotti CG, Boop FA, et al.  Nat Genet 2009 Apr;41(4):465-72. Epub 2009 Mar 8


Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Johnson R, Wright K, Poppleton H, Mohankumar K, Finkelstein D, Pounds S, Neale G, Wang Y, Coyle B, Atkinson J, DeWire M, Kranenburg T, Gillespie Y, Allen J, Merchant T, Boop FA, Sanford R, Gajjar A, Ellison D, Taylor M, Grundy R, Gilbertson R.   Nature ,29 July 2010, Vol 466,  632-636


Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Zhang  J, Wu G,  Miller C,  Tatevossian R, Dalton J, Tang B, Orisme W,   Punchihewa C, Parker M, Qaddoumi I,  Boop FA,  Lu C, Kandoth C,  Ding L,   Lee R, Huether R, Chen X, Hedlund E, Nagahawatte P, Rusch M, Boggs K,  Cheng J, Becksfort J, Ma J, Song G,  Yougjin L, Wei L, Wang J, Shurtleff S, Easton J, Zhao D,  Fulton R, Fulton L, Dooling D, Vadodaria B, Mulder H,   Tang C,  Ocha K, Mullighan C, Gajjar A, Kriwacki R, Sheer D,  Gilbertson R,  Mardis  E, Wilson R, Downing J, Baker S,  Ellison D; for the St. Jude Research Hospital Washington University Pediatric Cancer Genome Project:Journal nam Nature GeneticsYear published:; 201DOI:3  doi:10.1038/ng.2611, Epub 2013 April 14









C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma. Gilbertson R,  Parker M, Mohankumar K, Punchihewa C, Weinlich R, Dalton J,  Lee R, Tatevossian R,  Phoenix T, Thiruvenkatam R,  Lee Y,  White E, Tang B,  Orisme W,  Gupta K, Rusch M,  Chen X,  Nagahawhatte P, Hedlund Finkelstein

D,  Wu G, Shurtleff S, Easton J,  Boggs K,  Yergeau D,  Vadodaria B, Mulder H,   Becksfort J,  Gupta P,  Huether R, Ma J, Song G, Ding L, Lu C, Ochoa K,  Zhao D,  Fulton R,  Fulton L, Mardis E, Wilson R,  Downing J, Green D, Zhang J, Ellison D,  Li Y,  Gajjar A,  Merchant T,  Boop FA, Smith A [Paper #2013-02-

02831E], .Nature, Epub 2014 Feb 19


              Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas. Qaddoumi I1, Kocak M2, Pai Panandiker AS3, Armstrong GT4, Wetmore C1, Crawford JR5, Lin T2, Boyett JM2, Kun LE3, Boop FA6, Merchant TE3, Ellison DW7, Gajjar A1, Broniscer A1.Front Oncol. 2014 Apr 1;4:67 


Subsequent Neoplasms in Survivors of Central Nervous System Tumors: Risk After Modern Multi-modal Therapy,   Karen Tsui, MD¹, Amar Gajjar, MD¹, Chenghong Li², Deokumar Srivastava, PhD², Alberto Broniscer, MD¹, Cynthia Wetmore, MD, PhD¹, Larry E Kun, MD³, Thomas E. Merchant, DO, PhD³, David

W. Ellison, MD, PhD, Brent Orr, MD, PhD, Frederick A. Boop, MD⁵⁻⁷, Paul Klimo JR. MD⁵⁻⁷, Jordan D. Ross, BS8, Leslie L. Robison, PhD9, Gregory T. Armstrong, MD, Submitted Neuro-Oncology May 21, 2014




D.  Research Support.

Ongoing Research Support


“Investigating Physiological Functions and Pathological Alterations in Human Cerebral Arteries”, IRB Number 11-01628-XP 10/29/13- 11/29/14 Jonathan Jaggar PhD Principal Investigator,  Frederick A. Boop, M.D. Co-Principal Investigator


iRISE Pilot Projects Grant Program, Jonathan Jaggar PhD Principal Investigator, Frederick A. Boop, M.D. Co-Principal Investigator  1/1/15 to 12/31/15