Hamid Bassiri, MD
Disclosures: Nothing to disclose - 01/17/2020

Hamid Bassiri, MD, PhD is currently an Assistant Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania (Penn) and a faculty member in the Division of Infectious Diseases at the Children’s Hospital of Philadelphia (CHOP). Clinically, Dr. Bassiri specializes in the infectious care of immunocompromised hosts, especially those with primary immunodeficiencies, malignancy, or those undergoing hematopoietic stem cell or solid organ transplantation. He serves as the Program Director for CHOP's Pediatric Infectious Diseases fellowship. Dr. Bassiri has had a long-standing interest in understanding the mechanisms that regulate immune responses. He is currently the Co-Director of the Immune Dysregulation program at CHOP, where he and colleagues study the mechanisms of pediatric hyperinflammation seen in hemophagocytic lymphohistiocytosis (HLH), the cytokine release Syndrome (CRS) associated with the use of cellular cancer immunotherapies, and more recently, the multisystem inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection. Furthermore, as a member of the Center for Childhood Cancer Research, and the Immunology and Cancer Biology graduate groups, his research has also focused on understanding the biology and function of invariant natural killer (iNKT) cells and natural killer (NK) cells and the ways by which to harness the activity of these lymphocytes for cellular immunotherapy of pediatric solid tumors such as neuroblastoma. His lab also studies the ways in which the immunometabolic features of these different lymphocytes allow them to persist and function within solid tumors, and how modulation of these features may enhance anti-tumor immunity. He was recently named as the St. Jude-PIDS transplant and immunocompromised host research conference planning rising vice-chair, and also a member of the IDSA infectious complications associated with immunomodulatory therapies working group.

For further information, please see: https://www.med.upenn.edu/apps/faculty/index.php/g275/p33945

A complete list of his peer-reviewed publications can be found at: https://www.ncbi.nlm.nih.gov/myncbi/16QVsxj0b9JQv/bibliography/public/